Drug Interactions and Contraindications

1. Mr. Gagnon, 75 years old, takes warfarin for atrial fibrillation. During medication reconciliation, he mentions that he also takes aspirin daily for joint pain. What is the LPN’s best intervention? *
2. A hospitalized client is started on a monoamine oxidase inhibitor (MAOI) for the treatment of depression. The LPN should instruct the client that which foods are acceptable to consume while taking this medication? *
3. A client with type 2 diabetes and chronic kidney disease is prescribed metformin. The LPN reviews the lab results and notes an eGFR of 25 mL/min/1.73m² (Normal: 80-120 mL/min/1.73 m²). What should the LPN anticipate? *
4. A client taking lisinopril reports using an over-the-counter potassium supplement for leg cramps. What should concern the nurse? *
5. A 40-year-old client with asthma is prescribed propranolol for hypertension. What is the nurse’s priority concern? *
6. Mr. Lapointe, 60 years old, with angina is prescribed nitroglycerin for chest pain. He also takes sildenafil for erectile dysfunction. Why is this combination dangerous? *
7. A bipolar patient stabilized on lithium begins taking furosemide for edema. What effect may occur due to this combination? *
8. A client taking simvastatin reports drinking grapefruit juice every morning. What should the nurse teach? *
9. A nurse counsels a patient on warfarin who reports eating large amounts of spinach daily. What effect does this diet have on warfarin therapy? *
10. A patient with a history of gastric ulcers requests ibuprofen for joint pain. What is the safest nursing recommendation? *
11. A 70-year-old client with reduced ejection fraction heart failure is prescribed verapamil for arrhythmia. What should the nurse recognize? *
12. A patient taking tetracycline for infection also takes aluminum hydroxide for heartburn. What should the nurse instruct? *
13. A patient with rheumatoid arthritis on prednisone develops fever and cough. Why should this be reported immediately? *
14. A post-angioplasty patient is prescribed clopidogrel and omeprazole. Why is this combination concerning? *
15. A nurse prepares to administer furosemide to a patient with a documented sulfa allergy. What should the nurse do? *
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